If you're tired of saying "Can you hear me?" on your Android phone, a few settings can help. The most impactful are VoLTE and Wi-Fi calling, which route calls over faster data networks instead of older 2G/3G. VoLTE is usually in Settings > Network & Internet > Mobile network (or Connections > Mobile Networks on Samsung). Wi-Fi calling is under SIM settings or Connections > Wi-Fi Calling. Both improve clarity and connection speed, though availability varies by carrier and device.
For background noise, Pixel phones have Clear Calling (Settings > Sound & vibration > Clear Calling), available on Pixel 7 and later. Samsung's Mic mode, found in Quick settings during a call, offers Standard, Voice focus, or Full spectrum options on select newer Galaxy devices. These features filter noise or capture more of your voice, but they work differently across apps and devices.
To hear callers better, Samsung's Adapt sound (Settings > Sounds and vibration > Sound quality and effects) tunes audio to your ears via presets or a hearing test, but only with headphones. Pixel's Adaptive Sound adjusts speaker output based on your environment. Other Android phones may have similar options, so check your settings.
The source notes that call quality also depends on the other person's signal and environment, so not all issues are fixable on your end. If problems persist, clean your mic and speaker, and check if your case is blocking them.