Ars Technica reports on a case study in the New England Journal of Medicine involving a woman in the Philippines who experienced a sudden focal seizure. MRI revealed a cluster of nodules in her left frontal lobe, and doctors suspected neuroschistosomiasis, a rare complication of infection with Schistosoma japonicum, a parasitic blood fluke common in the Philippines.
A circumoval precipitin test, developed in the 1950s, produced tail-like structures on reference S. japonicum eggs when exposed to the woman's serum, confirming the infection. Stool analysis also found 190 eggs per gram of feces. After treatment with an anti-parasitic drug, an anti-inflammatory, and an anti-seizure medication, the woman reported no additional seizures at three months, and a follow-up MRI showed the eggs were gone.
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