Roughly one in four active-duty U.S. Army men had a single morning testosterone measurement below 300 ng/dL, the common threshold for low testosterone, according to a study in JAMA. The finding highlights a potential under-recognized issue in a young, physically active population.
Separately, a CDC report found that nearly half of American women aged 40 to 60 experienced menopausal symptoms in 2025, but only 15.6% of that group took prescription medications for them. In related GLP-1 research, Novo Nordisk reported that its investigational semaglutide-cagrilintide combination produced an average 25% weight loss in women, with similar results across pre-, peri-, and postmenopausal stages.
An analysis of Reddit posts about the unapproved weight-loss drug retatrutide found the most commonly reported adverse events included appetite increases, fatigue, increased energy, insomnia, elevated heart rate, and muscle-related symptoms. The source article also noted other endocrinology news, including a link between greater weight loss and larger blood pressure drops, and a new AI-driven obesity collaboration between Zealand Pharma and Generate Biomedicines.