A teenager who went into surgery for a broken arm emerged with brain damage, a case profiled by The Atlantic. The report does not specify the cause, but it highlights anesthesia safety as a continuing concern in routine procedures.
Two dementia-related findings appeared in the same roundup. A randomized trial in JAMA Neurology found that disclosing Alzheimer's biomarkers earlier improved diagnostic certainty and clinical management for patients being evaluated for cognitive symptoms. Meanwhile, a large U.S. population-based study in the Journal of Alzheimer's Disease reported that people who had obesity at dementia diagnosis lived longer than those of normal weight—an apparent obesity paradox.
Other studies covered include a novel antisense oligonucleotide designed for a single patient with CHCHD10-related ALS, which showed early signs of efficacy, and 10 years of continuous ocrelizumab in relapsing multiple sclerosis, which outperformed a two-year treatment delay. The Alzheimer's Association also launched a Brain Health & Quality Care Initiative to bring advances into practice.
Finally, actor Alan Alda discussed managing Parkinson's disease through laughter and connection. These items are drawn from a single MedPage Today roundup and are not directly related to one another.