A study in mice has linked the gradual loss of a brain protein called Menin to multiple hallmarks of aging. As Menin levels fell, the animals showed increased inflammation, cognitive decline, weaker bones, and thinner skin — suggesting the protein may help coordinate a broad aging response.
When researchers restored Menin in the mice, they observed a reversal of several age-related changes. The findings point to Menin as a potential therapeutic target, though the work is still at an early animal-model stage.
The same report also mentions the amino acid D-serine in connection with Menin's effects, but the details of that relationship are not fully described in the summary. No human trials or clinical implications are stated in the source.