Researchers at NYU Abu Dhabi, in partnership with Cleveland Clinic Abu Dhabi, have developed a seed-sized injectable device that can regulate nerve activity without surgical implantation, batteries, or connecting wires. The device is delivered through a standard needle and positioned close to a specific nerve, where it sends controlled electrical signals to alter that nerve's activity. Power comes from outside the body, allowing doctors or patients to adjust stimulation in real time.
The technology, described in Science Advances, is designed as an alternative to existing treatments such as medications and surgically implanted stimulators. Because it can be injected rather than implanted, it may reduce procedure-related risks and shorten recovery times. The device can also be located and monitored using familiar imaging techniques like ultrasound and CT scans, which help guide placement and verify its position afterward.
In laboratory and preclinical testing, the device delivered precise nerve stimulation and maintained consistent performance under conditions meant to mimic real-world use. The team also showed it could activate nerves in vivo, an early step toward eventual medical use. However, the device's ability to relieve chronic pain or improve movement disorders in human patients has not yet been established, and further research is needed to confirm safety and effectiveness before it could become a clinical option.