The latest TTHealthWatch podcast from Texas Tech reviewed two notable studies. One compared management strategies for early septic shock; the other examined menopausal hormone therapy and cardiovascular risk.
For septic shock, the primary endpoint was being alive and out of the hospital at day 90. The hosts reported that both strategies were equally effective, meaning clinicians can choose based on patient factors.
The hormone therapy analysis, based on Danish national registries, identified thousands of women with venous thromboembolism, ischemic stroke, or myocardial infarction. Oral estrogen specifically was linked to increased risk, reinforcing caution in prescribing.
The podcast also briefly covered lean MASLD and blood-based cancer screening, but the main takeaways for practice are the equivalence of septic shock strategies and the need to weigh oral estrogen's thromboembolic risk.