Swedish Trial Finds Mepivacaine Eases IUD Insertion Pain
A randomized trial from Sweden shows that placing the anesthetic mepivacaine inside the uterus reduces pain during IUD placement.
A Swedish randomized trial offers a new option for reducing the discomfort of intrauterine device insertion. Researchers found that instilling the local anesthetic mepivacaine directly into the uterus significantly decreased pain during the procedure.
Pain was measured using a visual analog scale, with a mean score of 43.8 mm during placement among participants who received the drug. The trial's results support intrauterine anesthetic instillation as a viable method for easing one of the most common barriers to IUD use.
Because this is a single source, there are no differing findings to compare. The study's authors reportedly suggest the technique could be a practical addition to standard IUD insertion protocols, though broader implementation will depend on further validation and clinical context.
More in Medicine & Biotech
Ebola Vaccine Trial Launches in DR Congo Outbreak Zone
Health workers in DR Congo have begun testing whether a vaccine designed for a different Ebola strain can protect against the current outbreak.
Beacon Gene Therapy for Rare Vision Loss Succeeds in Pivotal Trial
A pivotal trial of Beacon Therapeutics' gene therapy for X-linked retinitis pigmentosa improved visual acuity, clearing the path toward an FDA submission.
Alkermes orexin agonist shows early promise for ADHD
Early-stage data suggest Alkermes' orexin agonist could expand the drug class beyond sleep disorders into ADHD.
Telix to Buy ITM for $1.65B, Challenging Novartis in Radiopharma
The acquisition gives Telix a late-stage pipeline and supply network that could compete with Novartis' Lutathera.