Vertex's inaxaplin shows positive phase 2b data in kidney disease
New midstage results for Vertex's inaxaplin could expand its reach beyond the patient group targeted in the pivotal trial.
Medicine & Biotech
Clinical AI, drug discovery, devices, and regulatory approvals.
Bangladesh measles outbreak kills nearly 900, mostly children
A suspected measles outbreak in Bangladesh underscores the danger of slipping childhood vaccination rates.
HER2-Positive Gastroesophageal Cancer Care Shifts Rapidly
After years of stagnation, treatment for HER2-positive gastroesophageal adenocarcinoma has advanced quickly, with successive new standards of care emerging in the past five years.
First Mouse Model for DHDDS-Linked Encephalopathy Unveils Disease Mechanisms
A new mouse model that reproduces a rare genetic encephalopathy associated with the DHDDS gene gives researchers a tool to study how the disease develops.
Barzolvolimab impresses in hives but anaphylaxis cases alarm
New data show barzolvolimab may be the most effective treatment yet for chronic hives, but two life-threatening allergic reactions overshadow the results and raise regulatory hurdles.
Immune Cells Linked to Sustained Type 1 Diabetes Attack Identified
Researchers have identified immune cells that may explain why the autoimmune attack in type 1 diabetes persists for years.
Cardiologists Join USPSTF; Afib Stimulator, Tree Injury in Roundup
MedPage Today's roundup highlights two cardiologists appointed to the U.S. Preventive Services Task Force, alongside briefs on an atrial fibrillation device and a tree-related injury.
Pacemaker After TAVI Affects Women and Men Differently
A new study finds that the prognostic significance of a pacemaker after transcatheter aortic valve implantation differs by sex.
Hackensack Meridian CEO to retire; successor search begins
The leader of New Jersey's largest health system will step down next year, prompting a national search that is expected to conclude by early 2027.
Lindsay Clancy Case: Lawyer Seeks Probe of Juror Who Sought Conviction
A defense motion asks a judge to investigate the conduct of the lone juror who wanted to convict the Massachusetts mother.
Preclinical Study Offers Clue to Allergy Worsening With Repeat Exposure
A Mass General Brigham preclinical study proposes a shared explanation for delayed allergy onset and the development of multiple allergies.
Simple cleaning cuts bacteria on single-use devices, study finds
A University of Gothenburg study shows basic cleaning methods can reduce bacteria on single-use medical devices, offering a potential emergency fallback during supply shortages.
Texas HCA hospitals sue Independence Blue Cross over denied claims
Five HCA-affiliated Texas hospitals allege the BlueCard program still causes denied claims despite a $2.8B settlement.
Aging Smokers Explain Rising Five-Year Mortality Risk
The apparent increase in smokers' five-year death risk from 1987 to 2013 is driven by an older smoking population, not by cigarettes becoming deadlier.
AI assistant reads radiology reports to flag abdominal scan issues
An AI system that learns from radiology reports could help radiologists spot problems in complex abdominal CT scans.
Pelago Launches Integrated Behavioral Health Platform With AI Triage
The new platform combines substance use, mental health, and behavioral addiction care with AI-powered triage to route patients to appropriate treatment.
Older adults' medication access suffers without regular family doctor
A 65-year-old's experience illustrates how inconsistent primary care can disrupt routine prescriptions for common maintenance medications.
Ketamine-linked bladder damage seen in UK teens as young as 13
A UK clinic reports that non-prescribed ketamine use can lead to bladder problems starting as early as age 13, according to a new clinical letter.