MultiCare and Samaritan to Complete Merger on Nov. 1
The nonprofit health systems will combine after regulatory approval, with MultiCare investing $700 million into Samaritan over a decade.
Medicine & Biotech
Clinical AI, drug discovery, devices, and regulatory approvals.
Prostate Cancer Care: Weighing Treatment Side Effects and Quality of Life
An oncologist explains how patients with metastatic castration-sensitive prostate cancer can manage androgen deprivation therapy side effects while staying on continuous treatment.
Compass CEO urges cautious rollout for psychedelic depression therapy
Compass Pathways plans a slow launch for its psilocybin treatment while researchers warn that scientific questions remain.
US Heart Failure Patients Show High Inflammation Burden, Registry Finds
About half of U.S. heart failure patients in a large registry had elevated hsCRP, underscoring an unmet need for inflammation-targeting therapies.
Trial Stopped Early: Intermittent Dialysis Tied to Higher Deaths in AKI
The ICRAKI trial found that starting with intermittent hemodialysis increased mortality in critically ill patients with acute kidney injury, prompting early termination.
Real-World AMD Data Show Early Drop in Anti-VEGF Adherence
A large database review finds most wet AMD patients stop anti-VEGF injections within two years, while bevacizumab use is rising.
Ultragenyx Sells Two Rare Disease Vouchers for $413M
The cash haul gives Ultragenyx more financial flexibility to pursue another rare disease deal.
Oral Peptide Icotrokinra Shows Durable Ulcerative Colitis Response
Phase IIb data show most patients on the oral IL-23 receptor blocker maintained clinical response and remission through 76 weeks.
Long-Acting HIV Injection Matches Daily Pills in Adherence-Challenged Patients
A phase IIIb trial in Africa found injectable cabotegravir/rilpivirine was noninferior to oral dolutegravir-based therapy for viral suppression at 48 weeks.
CGM Cuts HbA1c in Type 2 Diabetes Without Insulin
A randomized primary-care trial found continuous glucose monitors improved glucose control in non-insulin-treated type 2 diabetes.
Trump administration delays rule on imported medicines by 90 days
The 90-day delay gives critics more time to fight a rule that could cut off access to cheaper drugs from Canada and overseas.
One in Six Patients Report Disrespectful Language in Medical Records
A nationally weighted survey finds that disrespectful language in medical records is not rare, and most patients believe it could lead to worse health outcomes.
CMS cuts ACA subsidies for 189K duplicate, deceased enrollees
The administration says the move saves $738 million in improper payments without stripping anyone of coverage.
Healthleap Raises $38M to Expand AI Screening in Hospitals
The startup will use new funding to broaden its EHR-based screening tool to more overlooked conditions in hospitalized patients.
Dobutamine Plus Norepinephrine Cuts AKI Risk in Septic Shock Surgery
Adding dobutamine to norepinephrine during surgical source control reduced 7-day postoperative acute kidney injury by 36% in a randomized trial.
CDC Backs Controversial Hepatitis B Vaccine Trial in Guinea-Bissau
The agency is funding a formerly suspended study that experts call unethical, according to a new policy roundup.
Verastem's KRAS G12D drug shows early promise across three tumor types
Early data suggest Verastem's VS-7375 could compete in the crowded KRAS G12D space, with response rates meeting or beating analyst expectations.
After RJ Mitte's Suicide, a Call to Rethink Men's Mental Health
A psychologist reflects on the actor's death by suicide to highlight how masculine norms and hidden distress put young men at risk.